the human immune system at a natural scale ImmunoGrid : towards agent - based simulations of
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, 2799-2815 368 2010 Phil. Trans. R. Soc. A Brusic and Adrian J. Shepherd Pier-Luigi Lollini, Annalisa Murgo, Arianna Palladini, Kaye E. Basford, Vladimir Massimo Bernaschi, Marie-Paule Lefranc, Søren Brunak, Ole Lund, Santo Motta, Olivo Miotto, Daniel Churchill, Elda Rossi, David S. Moss, Clare E. Sansom, Alemani, Andrew Emerson, Filippo Castiglione, Patrice Duroux, Marzio Pennisi, Mark Halling-Brown, Francesco Pappalardo, Nicolas Rapin, Ping Zhang, Davide the human immune system at a natural scale ImmunoGrid: towards agent-based simulations of
منابع مشابه
ImmunoGrid: towards agent-based simulations of the human immune system at a natural scale.
The ultimate aim of the EU-funded ImmunoGrid project is to develop a natural-scale model of the human immune system-that is, one that reflects both the diversity and the relative proportions of the molecules and cells that comprise it-together with the grid infrastructure necessary to apply this model to specific applications in the field of immunology. These objectives present the ImmunoGrid C...
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BY MARK HALLING-BROWN1, FRANCESCO PAPPALARDO2, NICOLAS RAPIN3, PING ZHANG4, DAVIDE ALEMANI5, ANDREW EMERSON6, FILIPPO CASTIGLIONE7, PATRICE DUROUX8, MARZIO PENNISI2, OLIVO MIOTTO9, DANIEL CHURCHILL10, ELDA ROSSI6, DAVID S. MOSS1, CLARE E. SANSOM1, MASSIMO BERNASCHI7, MARIE-PAULE LEFRANC8, SØREN BRUNAK3, OLE LUND3, SANTO MOTTA2, PIER-LUIGI LOLLINI11, ANNALISA MURGO11, ARIANNA PALLADINI11, KAYE E...
متن کاملImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design and optimization
Vaccine research is a combinatorial science requiring computational analysis of vaccine components, formulations and optimization. We have developed a framework that combines computational tools for the study of immune function and vaccine development. This framework, named ImmunoGrid combines conceptual models of the immune system, models of antigen processing and presentation, system-level mo...
متن کاملThe ImmunoGrid Simulator: How to Use It
In this paper we present the ImmunoGrid project, whose goal is to develop an immune system simulator which integrates molecular and system level models with Grid computing resources for large-scale tasks and databases. We introduce the models and the technologies used in the ImmunoGrid Simulator, showing how to use them through the ImmunoGrid web interface. The ImmunoGrid project has proved tha...
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Most infectious diseases are caused by pathogenic infiltrations from the mucosal tract. Nowadays, the use of vaccines has been widely investigated for the prevention of different infectious diseases, infertility, immune disorders, malignancies, and allergies. Broad-spectrum adjuvant substances have been studied for immune system stimulation with a greater efficiency against specific antigens. V...
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تاریخ انتشار 2010